Diagnosis and monitoring of patients with Parkinson's disease with the use of Smartphone
Keywords:
Parkinson, inteligencia artificial, aprendizaje automático, bradikinesia, temblor en reposo, rigidez muscular, inestabilidad postural, vozAbstract
Introduction: currently, many efforts are being made to achieve accurate medical diagnoses and subsequent patient follow-up. One of the diseases that has been the subject of research for this purpose is Parkinson's disease. Particularly in the area of artificial intelligence, and more specifically machine learning, several results have been shown to corroborate this.
Objective: to find evidence supporting the use of smartphones for data extraction and the main metrics and algorithms used to classify patients with this disease.
Methods: the PRISMA (2020) checklist was used to conduct the search. The search covered the last 6 years and included articles written in Spanish or English. Studies were selected from sources such as Scopus, PubMed, SciElo, IEEE, Google Scholar, and ACM. The last search was conducted in January 2025. To avoid review bias, only previously published articles were accepted, as well as those that could be viewed. Tools such as Mendeley, Excel, and descriptive statistics were used to synthesize the results.
Development: 72 articles were obtained that met the criteria for review, 20 of which used cell phones for data extraction and classification.
Conclusions: there is evidence supporting the use of smartphones for the classification of patients with Parkinson's disease. Among the most commonly used metrics are gait, tremor, bradykinesia, and in recent years, voice has been incorporated as an early assessment measure for this disease.
Downloads
References
Aich, S. (2020). A supervised machine learning approach to detect the on/off state in Parkinson’s disease using wearable based gait signals.
Aich, S. (2020). Design of a machine learning-assisted wearable accelerometer based a utomated system for studying the effect of dopa minergic medicine on.
Alshammri, R., Alharbi, G., Alharbi, E., & Almubark, I. (2023). Machine Learning approaches to identify Parkinson´s disease using voice signal features. Frontiers in Artificial Intelligence, 8.
Borzì, L., Varrecchia, M., Olmo, G., Artusi, C. A., Fabbri, M., Rizzone, M. G., . . . Lopiano, L. (2019). Home monitoring of motor fluctuations in Parkinson’s disease patients.
Erb, M. (2020). mHealth and wearable technology should replace motor diaries to track motor fluctuations in Parkinson’s disease. .
Espay, A. J. (2019). A roadmap for implementation of patient-centered digital outcome measures in Parkinson’s disease obtained using mobile health technologies.
Evers, L. (2020). Real-life gait performance as a digital biomarker for motor fluctuations: the Parkinson@Home validation study.
Feng Tian, X. F. (2019). What Can Gestures Tell?Dete cting Motor Impairment in Early Parkinson’s.
Feng, T., X. F., Junjun, F., Yicheng, Z., Gao, J., Wang, D., & Xiaojun Bi. (2019). What Can Gestures Tell? Detecting Motor Impairment in Early Parkinson’s from Common Touch Gestural Interactions.
Florian Lipsmeier, K. I.-E.-Y.-G.-P. (2019). Evaluation of Smartphone-Based Testing to Generate Exploratory Outcome Measures in a Phase 1 Parkinson’s Disease Clinical Trial.
García, B. (2019). Applied Machine Learning Techniques to Diagnose Voice-Affecting Conditions and Disorders: Systematic Literature Review.
Ghoraani, B., Hssayeni, M. D., Bruack, M. M., & Jimenez-Shahed, J. (2020). Multilevel features for sensor-based assessment of motor fluctuation in Parkinson’s disease subjects.
Gil-Martín, M., Montero, J. M., & San-Segundo, R. (2019). Parkinson’s Disease Detection from Drawing Movements Using Convolutional Neural Networks.
HANBIN ZHANG, C. X. (2019). PDMove: Towards Passive Medication Adherence Monitoring of Parkinson’s Disease Using Smartphone-based Gait Assessment.
HE LI, K. O. (2019). Deep Reinforcement Scheduling for Mobile Crowdsensing in Fog Computing.
Hssayeni, M. D., Jimenez-Shahed, J., Burack, M. A., & Ghoraani, B. (2019). Wearable sensors for estimation of parkinsonian tremor severity during free body movements.
Islam, M., H. M., Hussein, M., & Miah, M. S. (2024). A review of machine learning and deep learning algorithms for Parkinson’s disease detection using handwriting and voice datasets. Elsevier, 33.
Jeon, H. (2019). High-accuracy automatic classification of Parkinsonian tremor severity using machine learning method.
Lee, A. (2020). Can google glassTM technology improve freezing of gait in parkinsonism? A pilot study. .
Lo, C., fg, thu, y, yuh, yui, & iop. (2019). Predicting motor, cognitive & functional impairment in Parkinson’s.
Mahadevan, N. (2020). Development of digital biomarkers for resting tremor and bradykinesia using a wrist-worn wearable device. .
Marcante, A. (2020). Foot pressure wearable sensors for freezing of gait detection in Parkinson’s disease.
Murtadha D. Hssayeni, J. J.-S. (s.f.). Hybrid Feature Extraction for Detection of Degree of Motor Fluctuation Severity in Parkinson’s.
Nair, P., Trisno, R., Baghini, M. S., Pendharkar, G., & Chung, H. (2020). Predicting early stage drug induced parkinsonism using unsupervised and supervised machine learning.
Oyama, G. (2019). Analytical and clinical validity of wearable, multi sensor technology for assessment of motor function in patients with Parkinson’s disease in Japan.
Pfister, F. (2020). High-resolution motor state detection in Parkinson’s disease using convolutional neural networks.
Ray, S. (2019). A Predictive Diagnosis for Parkinson’s Disease Though Machine Learning.
Reches, T. (2020). Using wearable sensors and machine learning to automatically detect freezing of gait during a FOG-Provoking test.
Rehman, R. (2020). Accelerometry-based digital gait characteristics for classification of Parkinson’s disease: what counts?
Rodríguez-Molinero, A., gonzales, B., alvarez, C., Rap, F., Fru, t., rip, Y., & hjop, P. (2019). Estimating dyskinesia severity in Parkinson’s disease by using a waist-worn sensor: concurrent validity study.
Sajal, M. (2020). Telemonitoring Parkinson’s disease using machine learning by combining tremor and voice analysis.
Sherina T.M, M. S. (s.f.). A Survey on Machine Learning Techniques for Parkinson’s Disease Diagnosis and Classification.
Singh, S., & Xu, W. (2020). Robust detection of Parkinson’s disease using harvested smartphone voice data: a telemedicine approach.
Steinmetzer, T., Maasch, M., Bönninger, I., & Travieso, C. M. (2019). Analysis and Classification of Motor Dysfunctions in Arm Swing in Parkinson’s Disease.
Tiang, F. (2019). What Can Gestures Tell? Detecting Motor impairment in Early Parkinson’s from Common Touch Gestural Interactions.
Van Brummelen, E. (2020). Quantification of tremor using consumer product accelerometry is feasible in patients with essential tremor and Parkinson’s disease: a comparative study.
Vessio, G. (2019). Dynamic Handwriting Analysis for Neurodegenerative Disease Assessment: A Literary Review.
Vivar, G. (2019). Contrast and homogeneity feature analysis for classifying tremor.
A. H. Butt, E. R. (2018). Objective and automatic classifcation.
B.KALAISELVI, S. R. (2018). Accelorometer based Classification of Parkinson’s disease by measuring the harmonics using MATLAB.
C. Lainscsek, P. R. (2012). Finger tapping movements of Parkinson’s disease patients automatically rated using nonlinear delay differential equations.
Chae Young Lee, S. J.-K.-I. (2016). A Validation Study of a Smartphone-Based Finger Tapping Application for Quantitative Assessment of Bradykinesia in Parkinson’s Disease.
Clayton R. Pereira, S. A. (2017). Deep Learning-aided Parkinson’s Disease Diagnosis.
Dustin A. Heldman, U. E. (2017). Automated Motion Sensor Quantification of Gait and Lower Extremity Bradykinesia.
Feng Tian, X. F. (2019). What Can Gestures Tell?Dete cting Motor Impairment in Early Parkinson’s.
Feng Tian1, 2. X. (2019). What Can Gestures Tell? Detecting Motor Impairment in Early Parkinson’s from Common Touch Gestural Interactions.
Florian Lipsmeier, K. I.-E.-Y.-G.-P. (2019). Evaluation of Smartphone-Based Testing to Generate Exploratory Outcome Measures in a Phase 1 Parkinson’s Disease Clinical Trial.
HANBIN ZHANG, C. X. (2019). PDMove: Towards Passive Medication Adherence Monitoring of Parkinson’s Disease Using Smartphone-based Gait Assessment.
HE LI, K. O. (2019). Deep Reinforcement Scheduling for Mobile Crowdsensing in Fog Computing.
Luigi Borzì, M. V. (2019). Home monitoring of motor fluctuations in Parkinson’s disease patients.
Manuel Gil-Martín, J. M.-S. (2019). Parkinson’s Disease Detection from Drawing Movements Using Convolutional Neural Networks.
Maryam Mahsal Khan, A. M. (2018). Evolutionary Wavelet Neural Network.
Murtadha D. Hssayeni, J. J.-S. (2019). Hybrid Feature Extraction for Detection of Degree of Motor Fluctuation Severity in Parkinson’s.
Panagiotis Kassavetis, M. T. (2015). Developing a Tool for Remote Digital Assessment of Parkinson’s.
Rachel Saunders-Pullman, C. D. (2008). Validity of Spiral Analysis in Early Parkinson’s Disease.
Ray, S. (2019). A Predictive Diagnosis for Parkinson’s Disease Though Machine Learning.
Robert I. Griffiths, K. K. (2012). Automated Assessment of Bradykinesia and Dyskinesia in Parkinson’s Disease.
Sherina T.M, M. S. (2019). A Survey on Machine Learning Techniques for Parkinson’s Disease Diagnosis and Classification.
Vessio, G. (2019). Dynamic Handwriting Analysis for Neurodegenerative Disease Assessment: A Literary Review.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 Revista Cubana de Neurologia y Neurocirugia

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

