MR imaging and spectroscopy at 7 Tesla

Authors

  • Peter B. Barker

Keywords:

Magnetic resonance, Spectroscopy

Abstract

Clinical MRI studies are generally performed at field strengths of either 1.5 or 3T. Increasing the magnetic field strength increases the size of the MR signal, allowing images to be recorded at higher spatial resolution, or in a shorter scan time with the same quality. For MR spectroscopy (MRS), there is an additional advantage that the spectral resolution increases, allowing more compounds to be detected, and more accurately quantified. However, many technical challenges have to be overcome in order to fully realize the expected advantages of higher magnetic fields. This presentation will review MRI and MRS for studies of the human brain at 7T. Some technical issues will be discussed, as well as example applications in neurodegenerative disease (Huntington’s disease) and schizophrenia.

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References

Oeltzschner G, Puts NA, Chan KL, Boer VO, Barker PB, Edden RA. Dual-volume excitation and parallel reconstruction for J-difference-edited MR spectroscopy. Magn Reson Med. 2016 Nov 8. doi: 10.1002/mrm.26536.

Brandt AS, Unschuld PG, Pradhan S, Lim IA, Churchill G, Harris AD, et al. Age-related changes in anterior cingulate cortex glutamate in schizophrenia: A (1)H MRS Study at 7 Tesla. Schizophr Res. 2016 Apr;172(1-3):101-5. doi: 10.1016/j.schres.2016.02.017.

Pradhan S, Bonekamp S, Gillen JS, Rowland LM, Wijtenburg SA, Edden RA, et al. Comparison of single voxel brain MRS AT 3T and 7T using 32-channel head coils. Magn Reson Imaging. 2015 Oct;33(8):1013-8. doi: 10.1016/j.mri.2015.06.003.

Published

2016-12-20

How to Cite

1.
Barker PB. MR imaging and spectroscopy at 7 Tesla. Rev Cubana Neurol Neurocir [Internet]. 2016 Dec. 20 [cited 2025 Jul. 3];6(1):S25. Available from: https://revneuro.sld.cu/index.php/neu/article/view/237